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1

Recent advances in transthyretin amyloidosis therapy

Ueda, Mitsuharu, Ando, Yukio

Journal:

Translational Neurodegeneration

Year:

2014

Language:

english

File:

PDF, 1.17 MB

english, 2014

2

Muscular amyloid angiopathy with amyloidgenic transthyretin Ser50Ile and Tyr114Cys

Taro Yamashita, Yukio Ando, Shoichi Katsuragi, Masaaki Nakamura, Konen Obayashi, Katsuki Haraoka, Mitsuharu Ueda, Sun Xuguo, Sadahisa Okamoto, Makoto Uchino

Journal:

Year:

2005

Language:

english

File:

PDF, 261 KB

english, 2005

3

Amyloid neuropathy in a younger domino liver transplanted recipient

Konen Obayashi, Taro Yamashita, Masayoshi Tasaki, Mitsuharu Ueda, Makoto Shono, Hirofumi Jono, Toshinori Ohshima, Yuki Ohya, Katsuhiro Asonuma, Yukihiro Inomata, Yukio Ando

Journal:

Year:

2011

Language:

english

File:

PDF, 173 KB

english, 2011

4

Wild-type transthyretin-derived amyloidosis in various ligaments and tendons

Takanao Sueyoshi, Mitsuharu Ueda, Hirofumi Jono, Hiroki Irie, Akira Sei, Junji Ide, Yukio Ando, Hiroshi Mizuta

Journal:

Human Pathology

Year:

2011

Language:

english

File:

PDF, 549 KB

english, 2011

5

Distinct characteristics of amyloid deposits in early- and late-onset transthyretin Val30Met familial amyloid polyneuropathy

Haruki Koike, Yukio Ando, Mitsuharu Ueda, Yuichi Kawagashira, Masahiro Iijima, Junko Fujitake, Michiyuki Hayashi, Masahiko Yamamoto, Eiichiro Mukai, Tomohiko Nakamura, Masahisa Katsuno, Naoki Hattori,

Journal:

Journal of the Neurological Sciences

Year:

2009

Language:

english

File:

PDF, 1.03 MB

english, 2009

6

Dominant cardiac type of familial amyloidotic polyneuropathy associated with a novel transthyretin variant Thr59Arg

Obayashi, Konen, Misumi, Yohei, Watanabe, Tetsuya, Ando, Tomotaka, Akagami, Takafumi, Tasaki, Masayoshi, Shinriki, Satoru, Ueda, Mitsuharu, Yamashita, Taro, Hirotani, Shinichi, Ando, Yukio

Journal:

Year:

2013

Language:

english

File:

PDF, 134 KB

english, 2013

7

Effects of tafamidis treatment on transthyretin (TTR) stabilization, efficacy, and safety in Japanese patients with familial amyloid polyneuropathy (TTR-FAP) with Val30Met and non-Varl30Met: A phase III, open-label study

Yukio, Ando, Yoshiki, Sekijima, Konen, Obayashi, Taro, Yamashita, Mitsuharu, Ueda, Yohei, Misumi, Hiroshi, Morita, Katsuyuki, Machii, Makoto, Ohta, Ami, Takata, Shû-ichi, Ikeda

Journal:

Journal of the Neurological Sciences

Year:

2016

Language:

english

File:

PDF, 492 KB

english, 2016

8

Shikonin, dually functions as a proteasome inhibitor and a necroptosis inducer in multiple myeloma cells

Wada, Naoko, Kawano, Yawara, Fujiwara, Shiho, Kikukawa, Yoshitaka, Okuno, Yutaka, Tasaki, Masayoshi, Ueda, Mitsuharu, Ando, Yukio, Yoshinaga, Kazuya, Ri, Masaki, Iida, Shinsuke, Nakashima, Takayuki, S

Journal:

International Journal of Oncology

Year:

2014

Language:

english

File:

PDF, 743 KB

english, 2014

9

9. Up-to-date Examinations in Neurological Disorders.

Ando, Yukio, Obayashi, Konen, Ueda, Mitsuharu

Journal:

Nihon Naika Gakkai Zasshi

Year:

2011

File:

PDF, 666 KB

2011

10

Clinicopathological characteristics of a patient with ureteral amyloidosis

Yanagisawa, Yukako, Obayashi, Konen, Tasaki, Masayoshi, Izaki, Ayane, Masuda, Teruaki, Misumi, Yohei, Ueda, Mitsuharu, Yamashita, Taro, Ando, Yukio

Journal:

Year:

2017

Language:

english

File:

PDF, 453 KB

english, 2017

11

Sushi repeat-containing protein 1: a novel disease-associated molecule in cerebral amyloid angiopathy

Inoue, Yasuteru, Ueda, Mitsuharu, Tasaki, Masayoshi, Takeshima, Akari, Nagatoshi, Akihito, Masuda, Teruaki, Misumi, Yohei, Kosaka, Takayuki, Nomura, Toshiya, Mizukami, Mayumi, Matsumoto, Sayaka, Yamas

Journal:

Acta Neuropathologica

Year:

2017

Language:

english

File:

PDF, 1.10 MB

english, 2017

12

Diagnosis and management of transthyretin familial amyloid polyneuropathy in Japan: red-flag symptom clusters and treatment algorithm

Sekijima, Yoshiki, Ueda, Mitsuharu, Koike, Haruki, Misawa, Sonoko, Ishii, Tomonori, Ando, Yukio

Journal:

Orphanet Journal of Rare Diseases

Year:

2018

Language:

english

File:

PDF, 1.33 MB

english, 2018

13

Patisiran, an RNAi Therapeutic, for Hereditary Transthyretin Amyloidosis

Adams, David, Gonzalez-Duarte, Alejandra, O’Riordan, William D., Yang, Chih-Chao, Ueda, Mitsuharu, Kristen, Arnt V., Tournev, Ivailo, Schmidt, Hartmut H., Coelho, Teresa, Berk, John L., Lin, Kon-Ping,

Journal:

New England Journal of Medicine

Year:

2018

Language:

english

File:

PDF, 367 KB

english, 2018

14

New simple and quick method to analyze serum variant transthyretins: direct MALDI method for the screening of hereditary transthyretin amyloidosis

Nomura, Toshiya, Ueda, Mitsuharu, Tasaki, Masayoshi, Misumi, Yohei, Masuda, Teruaki, Inoue, Yasuteru, Tsuda, Yukimoto, Okada, Masamitsu, Okazaki, Takahiro, Kanenawa, Kyosuke, Isoguchi, Aito, Nakamura,

Journal:

Orphanet Journal of Rare Diseases

Year:

2019

Language:

english

File:

PDF, 878 KB

english, 2019

15

Correction to: Diagnosis and management of transthyretin familial amyloid polyneuropathy in Japan: red-flag symptom clusters and treatment algorithm

Sekijima, Yoshiki, Ueda, Mitsuharu, Koike, Haruki, Misawa, Sonoko, Ishii, Tomonori, Ando, Yukio

Journal:

Orphanet Journal of Rare Diseases

Year:

2019

File:

PDF, 257 KB

2019

16

Green fluorescent protein-based lactate and pyruvate indicators suitable for biochemical assays and live cell imaging

Harada, Kazuki, Chihara, Takami, Hayasaka, Yuki, Mita, Marie, Takizawa, Mai, Ishida, Kentaro, Arai, Mary, Tsuno, Saki, Matsumoto, Mitsuharu, Ishihara, Takeshi, Ueda, Hiroshi, Kitaguchi, Tetsuya, Tsubo

Journal:

Scientific Reports

Year:

2020

File:

PDF, 1.10 MB

2020

17

Facile synthesis of p-tert-butylthiacalix[4]arene by the reaction of p-tert-butylphenol with elemental sulfur in the presence of a base

Hitoshi Kumagai, Mitsuharu Hasegawa, Setsuko Miyanari, Yoshihiro Sugawa, Yoko Sato, Takashi Hori, Sanae Ueda, Hiroki Kamiyama, Sotaro Miyano

Journal:

Tetrahedron Letters

Year:

1997

Language:

english

File:

PDF, 144 KB

english, 1997

18

Imaging of hydroperoxides in a rat glomerulus stimulated by puromycin aminonucleoside

Aoyagi, Kazumasa, Akiyama, Kayo, Tomida, Chie, Gotoh, Mitihiro, Hirayama, Aki, Takemura, Katsumi, Ueda, Atsushi, Nagase, Sohji, Koyama, Akio, Narita, Mitsuharu

Journal:

Kidney International

Year:

1999

Language:

english

File:

PDF, 125 KB

english, 1999

19

Chain reaction of amyloid fibril formation with induction of basement membrane in familial amyloidotic polyneuropathy

Yohei Misumi, Yukio Ando, Mitsuharu Ueda, Konen Obayashi, Hirofumi Jono, Yu Su, Taro Yamashita, Makoto Uchino

Journal:

The Journal of Pathology

Year:

2009

Language:

english

File:

PDF, 651 KB

english, 2009

20

Interleukin-6 signalling regulates vascular endothelial growth factor-C synthesis and lymphangiogenesis in human oral squamous cell carcinoma

Satoru Shinriki, Hirofumi Jono, Mitsuharu Ueda, Kazutoshi Ota, Tomoko Ota, Takanao Sueyoshi, Yuichi Oike, Mutsuko Ibusuki, Akimitsu Hiraki, Hideki Nakayama, Masanori Shinohara, Yukio Ando

Journal:

The Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 7.20 MB

english, 2011

21

A rapid and sensitive prenatal diagnosis of familial amyloidotic polyneuropathy ATTR Val30Met by mass spectrometry

Taro Yamashita, Yukio Ando, Mitsuharu Ueda, Sadahisa Okamoto, Yohei Misumi, Masaaki Nakamura, Ohba Takashi, Makoto Uchino

Journal:

Prenatal Diagnosis

Year:

2009

Language:

english

File:

PDF, 93 KB

english, 2009

22

Inhibitory effect of α-tocopherol on methylmercury-induced oxidative steress

Taro Yamashita, Yukio Ando, Masaaki Nakamura, Konen Obayashi, Hisayasu Terazaki, Katsuki Haraoka, Sun Xu Guo, Mitsuharu Ueda, Makoto Uchino

Journal:

Environmental Health and Preventive Medicine

Year:

2004

Language:

english

File:

PDF, 279 KB

english, 2004

23

Renal amyloidosis caused by apolipoprotein A-II without a genetic mutation in the coding sequence

Ryuji Morizane, Toshiaki Monkawa, Konosuke Konishi, Akinori Hashiguchi, Mitsuharu Ueda, Yukio Ando, Hirobumi Tokuyama, Koichi Hayashi, Matsuhiko Hayashi, Hiroshi Itoh

Journal:

Clinical and Experimental Nephrology

Year:

2011

Language:

english

File:

PDF, 2.18 MB

english, 2011

24

Multicenter evaluation of prototype real-time PCR assays for Epstein-Barr virus and cytomegalovirus DNA in whole blood samples from transplant recipients

Yoshinori Ito, Shunji Takakura, Satoshi Ichiyama, Mitsuharu Ueda, Yukio Ando, Kazuyuki Matsuda, Eiko Hidaka, Kaname Nakatani, Junji Nishioka, Tsutomu Nobori, Naoki Kajiyama, Hiroshi Kimura

Journal:

Microbiology and Immunology

Year:

2010

Language:

english

File:

PDF, 415 KB

english, 2010

25

Midkine in plasma as a novel breast cancer marker

Mutsuko Ibusuki, Hiromi Fujimori, Yutaka Yamamoto, Kazutoshi Ota, Mitsuharu Ueda, Satoru Shinriki, Masahiro Taketomi, Sadatoshi Sakuma, Masanori Shinohara, Hirotaka Iwase, Yukio Ando

Journal:

Year:

2009

Language:

english

File:

PDF, 348 KB

english, 2009

26

Effect of tacrolimus and partial hepatectomy on transthyretin metabolism in rats

Manuel E. Zeledon R., Yukio Ando, Katsuhiro Asonuma, Masaaki Nakamura, Xuguo Sun, Mitsuharu Ueda, Junko Fujii, Yukihiro Inomata

Journal:

Transplant International

Year:

2006

Language:

english

File:

PDF, 130 KB

english, 2006

27

Aberrant expression of serum amyloid A in head and neck squamous cell carcinoma

Satoru Shinriki, Mitsuharu Ueda, Kazutoshi Ota, Masaaki Nakamura, Mareina Kudo, Mutsuko Ibusuki, Jaemi Kim, Yoshihiro Yoshitake, Daiki Fukuma, Hirofumi Jono, Jun-ichi Kuratsu, Masanori Shinohara, Yuki

Journal:

Journal of Oral Pathology & Medicine

Year:

2010

Language:

english

File:

PDF, 333 KB

english, 2010

28

Loss of functional albumin triggers acceleration of transthyretin amyloid fibril formation in familial amyloidotic polyneuropathy

Kugimiya, Tomoe, Jono, Hirofumi, Saito, Shiori, Maruyama, Toru, Kadowaki, Daisuke, Misumi, Yohei, Hoshii, Yoshinobu, Tasaki, Masayoshi, Su, Yu, Ueda, Mitsuharu

Journal:

Laboratory Investigation

Year:

2011

Language:

english

File:

PDF, 326 KB

english, 2011

29

Hepatic Stellate Cells Accelerate the Malignant Behavior of Cholangiocarcinoma Cells

Hirohisa Okabe, Toru Beppu, Hiromitsu Hayashi, Takatoshi Ishiko, Toshiro Masuda, Ryu Otao, Hasita Horlad, Hirohumi Jono, Mitsuharu Ueda, Satoru Shinriki PhD, Yukio Ando, Hideo Baba

Journal:

Annals of Surgical Oncology

Year:

2011

Language:

english

File:

PDF, 576 KB

english, 2011

30

Identification of CXCL5/ENA-78 as a factor involved in the interaction between cholangiocarcinoma cells and cancer-associated fibroblasts

Hirohisa Okabe, Toru Beppu, Mitsuharu Ueda, Hiromitsu Hayashi, Takatoshi Ishiko, Toshiro Masuda, Ryu Otao, Hasita Horlad, Kosuke Mima, Keisuke Miyake, Masaaki Iwatsuki, Yoshifumi Baba, Hiroshi Takamor

Journal:

International Journal of Cancer

Year:

2012

Language:

english

File:

PDF, 1.28 MB

english, 2012

31

Manifestations of transthyretin-related familial amyloidotic polyneuropathy: Long-term follow-up of Japanese patients after liver transplantation

Yuki Ohya, Sadahisa Okamoto, Masayoshi Tasaki, Mitsuharu Ueda, Hirofumi Jono, Konen Obayashi, Kazuhisa Takeda, Hideaki Okajima, Katsuhiro Asonuma, Ryuhei Hara, Hidenobu Tanihara, Yukio Ando, Yukihiro

Journal:

Year:

2011

Language:

english

File:

PDF, 190 KB

english, 2011

32

Midkine expression in malignant salivary gland tumors and its role in tumor angiogenesis

Tomoko Ota, Kazutoshi Ota, Hirofumi Jono, Hiromi Fujimori, Mitsuharu Ueda, Satoru Shinriki, Takanao Sueyoshi, Masanori Shinohara, Yukio Ando

Journal:

Year:

2010

Language:

english

File:

PDF, 653 KB

english, 2010

33

Neointimal formation at the sites of anastomosis of the internal thoracic artery grafts after coronary artery bypass grafting in human subjects: An immunohistochemical analysis

Mitsuharu Hosono, Makiko Ueda, Shigefumi Suehiro, Yasuyuki Sasaki, Toshihiko Shibata, Koji Hattori, Hiroaki Kinoshita

Journal:

The Journal of Thoracic and Cardiovascular Surgery

Year:

2000

Language:

english

File:

PDF, 911 KB

english, 2000

34

Three-dimensional imaging of a tissuelike phantom by diffusion optical tomography

Ueda, Yukio, Ohta, Kazuyoshi, Oda, Motoki, Miwa, Mitsuharu, Tsuchiya, Yutaka, Yamashita, Yutaka

Journal:

Year:

2001

Language:

english

File:

PDF, 1.39 MB

english, 2001

35

Comparison of autonomic dysfunction in familial amyloidotic polyneuropathy Val30Met, Ser50Ile, and Tyr114Cys

Sadahisa Okamoto, Taro Yamashita, Konen Obayashi, Mitsuharu Ueda, Tomoo Hirahara, Akihiko Ueda, Yohei Misumi, Masaaki Nakamura, Yukio Ando, Makoto Uchino

Journal:

Autonomic Neuroscience

Year:

2007

Language:

english

File:

PDF, 47 KB

english, 2007

36

Improvement of autonomic dysfunction in patients with liver-transplanted familial amyloidotic polyneuropathy (FAP)

Yukio Ando, Konen Obayashi, Masaaki Nakamura, Taro Yamashita, Mitsuharu Ueda, Akihiko Ueda, Youhei Misumi, Sadahisa Okamoto

Journal:

Autonomic Neuroscience

Year:

2007

Language:

english

File:

PDF, 56 KB

english, 2007

37

A transgenic rat with the human ATTR V30M: A novel tool for analyses of ATTR metabolisms

Mitsuharu Ueda, Yukio Ando, Yoji Hakamata, Masaaki Nakamura, Taro Yamashita, Konen Obayashi, Shingo Himeno, Seiichiro Inoue, Yuki Sato, Takashi Kaneko, Nobutoki Takamune, Shogo Misumi, Shozo Shoji, Ma

Journal:

Biochemical and Biophysical Research Communications

Year:

2007

Language:

english

File:

PDF, 411 KB

english, 2007

38

Transmission of circulating cell-free AA amyloid oligomers in exosomes vectors via a prion-like mechanism

Masayoshi Tasaki, Mitsuharu Ueda, Sho Ochiai, Yuko Tanabe, Sho Murata, Yohei Misumi, Yu Su, Xuguo Sun, Satoru Shinriki, Hirofumi Jono, Makoto Shono, Konen Obayashi, Yukio Ando

Journal:

Biochemical and Biophysical Research Communications

Year:

2010

Language:

english

File:

PDF, 396 KB

english, 2010

39

Therapeutic approaches targeting midkine suppress tumor growth and lung metastasis in osteosarcoma

Takanao Sueyoshi, Hirofumi Jono, Satoru Shinriki, Kazutoshi Ota, Tomoko Ota, Masayoshi Tasaki, Eri Atsuyama, Toshitake Yakushiji, Mitsuharu Ueda, Konen Obayashi, Hiroshi Mizuta, Yukio Ando

Journal:

Year:

2012

Language:

english

File:

PDF, 1014 KB

english, 2012

40

Impact of serotonin transporter and catechol-O-methyl transferase genes polymorphism on gastrointestinal dysfunction in Swedish and Japanese familial amyloidotic polyneuropathy patients

Konen Obayashi, Malin Olsson, Intissar Anan, Mitsuharu Ueda, Masaaki Nakamura, Sadahisa Okamoto, Taro Yamashita, Takashi Miida, Yukio Ando, Ole B. Suhr

Journal:

Clinica Chimica Acta

Year:

2008

Language:

english

File:

PDF, 175 KB

english, 2008

41

Relationship between amyloid deposition and intracellular structural changes in familial amyloidotic polyneuropathy

Yohei Misumi, Mitsuharu Ueda, Konen Obayashi, Hirofumi Jono, Yu Su, Taro Yamashita, Toshinori Ohshima, Yukio Ando, Makoto Uchino

Journal:

Human Pathology

Year:

2012

Language:

english

File:

PDF, 2.93 MB

english, 2012

42

Mortality and morbidity after total arch replacement using a branched arch graft with selective antegrade cerebral perfusion

Toshihiko Ueda, Hideyuki Shimizu, Kenichi Hashizume, Kiyoshi Koizumi, Mitsuharu Mori, Hankei Shin, Ryohei Yozu

Journal:

The Annals of Thoracic Surgery

Year:

2003

Language:

english

File:

PDF, 103 KB

english, 2003

43

Discovery and preclinical profile of teneligliptin (3-[(2S,4S)-4-[4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl]pyrrolidin-2-ylcarbonyl]thiazolidine): A highly potent, selective, long-lasting and orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes

Tomohiro Yoshida, Fumihiko Akahoshi, Hiroshi Sakashita, Hiroshi Kitajima, Mitsuharu Nakamura, Shuji Sonda, Masahiro Takeuchi, Yoshihito Tanaka, Naoko Ueda, Sumie Sekiguchi, Takayuki Ishige, Kyoko Shim

Journal:

Bioorganic & Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 1.42 MB

english, 2012

44

Novel function of transthyretin in pancreatic alpha cells

Yu Su, Hirofumi Jono, Yohei Misumi, Takafumi Senokuchi, Jianying Guo, Mitsuharu Ueda, Satoru Shinriki, Masayoshi Tasaki, Makoto Shono, Konen Obayashi, Kazuya Yamagata, Eiichi Araki, Yukio Ando

Journal:

Year:

2012

Language:

english

File:

PDF, 978 KB

english, 2012

45

Increased expression of T cell activation markers (CD25, CD26, CD40L and CD69) in atherectomy specimens of patients with unstable angina and acute myocardial infarction

Mitsuharu Hosono, Onno J de Boer, Allard C van der Wal, Chris M van der Loos, Peter Teeling, Jan J Piek, Makiko Ueda, Anton E Becker

Journal:

Atherosclerosis

Year:

2003

Language:

english

File:

PDF, 400 KB

english, 2003

46

Marked cardiomegaly in a patient with familial amyloidotic polyneuropathy after orthotopic liver transplantation: a case study

Sakashita, Naomi, Kagawa, Seiko, Date, Risako, Ueno, Tatsuro, Nakagawa, Takenobu, Yamashita, Taro, Obayashi, Konen, Ohshima, Toshinori, Ueda, Mitsuharu, Horiguchi, Hidehisa, Ando, Yukio, Takeya, Motoh

Journal:

Pathology International

Year:

2013

Language:

english

File:

PDF, 1.52 MB

english, 2013

47

Cyclodextrin, a novel therapeutic tool for suppressing amyloidogenic transthyretin misfolding in transthyretin-related amyloidosis

Jono, Hirofumi, Anno, Takayuki, Motoyama, Keiichi, Misumi, Yohei, Tasaki, Masayoshi, Oshima, Toshinori, Mori, Yoshimasa, Mizuguchi, Mineyuki, Ueda, Mitsuharu, Shono, Makoto, Obayashi, Konen, Arima, Hi

Journal:

Biochemical Journal

Year:

2011

Language:

english

File:

PDF, 1013 KB

english, 2011

48

Effect of age and sex differences on wild-type transthyretin amyloid formation in familial amyloidotic polyneuropathy: A proteomic approach

Tasaki,, Masayoshi, Ueda, Mitsuharu, Obayashi, Konen, Koike, Haruki, Kitagawa, Keisuke, Ogi, Yasuhiro, Jono, Hirofumi, Su, Yu, Suenaga, Genki, Oshima, Toshinori, Misumi, Yohei, Yoshida, Mari, Yamashit

Journal:

International Journal of Cardiology

Year:

2013

Language:

english

File:

PDF, 579 KB

english, 2013

49

Notes, Short Comments, and Answers to Correspondents.

Isono, Kaori, Jono, Hirofumi, Ohya, Yuki, Shiraki, Nobuaki, Yamazoe, Taiji, Sugasaki, Ayaka, Era, Takumi, Fusaki, Noemi, Tasaki, Masayoshi, Ueda, Mitsuharu, Shinriki, Satoru, Inomata, Yukihiro, Kume,

Journal:

Year:

1899

Language:

english

File:

PDF, 839 KB

english, 1899

50

Generation of familial amyloidotic polyneuropathy-specific induced pluripotent stem cells

Isono, Kaori, Jono, Hirofumi, Ohya, Yuki, Shiraki, Nobuaki, Yamazoe, Taiji, Sugasaki, Ayaka, Era, Takumi, Fusaki, Noemi, Tasaki, Masayoshi, Ueda, Mitsuharu, Shinriki, Satoru, Inomata, Yukihiro, Kume,

Journal:

Stem Cell Research

Year:

2014

Language:

english

File:

PDF, 1.08 MB

english, 2014

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